Jordan R. Yaron, PhD

Curriculum Vitae (PDF)

Google Scholar
ResearchGate
Twitter: @jordanyaron
Instagram: @jordanyaron

Current Position

Assistant Research Professor
Rege Bioengineering Lab
School for Engineering of Matter, Transport, and Energy
Ira A. Fulton Schools of Engineering
Arizona State University
Faculty Page at ASU Biodesign

Education

Doctor of Philosophy, Biological Design
Arizona State University, April 2015
Dissertation: "Ion Flux Regulates Inflammasome Signaling"

Bachelors of Science, Biological Sciences - Genetics, Cell and Developmental Biology
Arizona State University, May 2010
Summa cum laude
Barrett Honors College Thesis: "Automated Confocal Microscopy Assay: Studying Heterogeneity and Toxic Variability in Neoplastic Progression of Barrett's Esophagus Cells"

Publications

  1. Kwiecien JM, Dabrowski W, Kwiecien-Delaney BJ, Kwiecien-Delaney CJ, Siwicka-Gieroba D, Yaron JR, Zhang L, Delaney KH, Lucas AR (2020). Neuroprotective Effect of Subdural Infusion of Serp-1 in Spinal Cord Trauma.
    Biomedicines. 8(10), 372.
  2. Kwiecien JM, Dabrowski W, Yaron JR, Zhang L, Delaney KH, Lucas AR (2020). The Role of Astrogliosis in Formation of the Syrinx in spinal cord injury.
    Current Neuropharmacology. In Press.
  3. Ghosh D, Godeshala S, Nitiyanandan R, Islam MS, Yaron JR, DiCaudo D, Kilbourne J, Rege K (2020). Copper-Eluting Fibers for Enhanced Tissue Sealing and Repair.
    ACS Applied Materials & Interfaces. 12(25), 27951-27960
  4. Kwiecien JM✝, Zhang L✝, Yaron JR✝, Schutz LN, Kwiecien-Delaney CJ, Awo EA, Burgin M, Dabrowski W, Lucas AR (2020). Local Chitosan-Serpin Injection after Spinal Cord Injury Reduces Inflammatory Damage and Improves Neurologic Function.
    Journal of Clinical Medicine. 9(4), 1221 (✝Equal Contributions)
  5. Yaron JR✝, Zhang L✝, Guo Q, Burgin M, Schutz L, Awo E, Wise L, Krause KL, Ildefonso CJ, Kwiecien JM, Juby M, Rahman MM, Chen H, Moyer RW, Alcami A, McFadden G, Lucas AR (2020). Deriving Immune Modulating Drugs from Viruses - A New Class of Biologics.
    Journal of Clinical Medicine. 9(4), 972 (✝Equal Contributions)
  6. Kwiecien JM, Dabrowski W, Dabrowska-Bouta B, Sulkowski G, Oakden W, Kwiecien-Delaney CJ, Yaron JR, Zhang L, Schutz L, Marzec-Kotarska B, Stanisz GJ, Karis JP, Struzynska L, Lucas AR (2020). Prolonged inflammation leads to ongoing damage after spinal cord injury.
    PLoS ONE. 15(3), e0226584 (bioRxiv)
  7. Yaron JR✝, Ambadapadi S✝, Zhang L, Chavan RN, Tibbetts SA, Keinan S, Varsani A, Maldonado J, Kraberger S, Tafoya AM, Bullard WL, Kilbourne J, Stern-Harbutte A, Krajmalnik-Brown R, Munk BH, Koppang EO, Lim ES, Lucas AR (2020). Immune protection is dependent on the gut microbiome in a lethal mouse gammaherpesviral infection.
    Scientific Reports. 10(1), 1-13 (✝Equal Contributions)
  8. Khatua B, Yaron J, El-Kurdi B, Kostenko S, Papachristou GI, Singh VP. Ringer's lactate prevents early organ failure by providing extracellular calcium.
    Journal of Clinical Medicine. 9(1), 263
  9. Zhang L✝, Yaron JR✝, Tafoya AM, Wallace SE, Kilbourne J, Haydel S, Rege K, McFadden G, Lucas AR (2019). A virus-derived immune modulating SERPIN accelerates wound closure with improved collagen remodeling.
    Journal of Clinical Medicine. 8(1626), 1-17 (✝Equal Contributions)
  10. Yaron JR✝, Chen H✝, Ambadapadi S✝, Zhang L, Tafoya AM, Munk BH, Wakefield D, Fuentes J, Marques BJ, Harripersaud K, Bartee MY, Davids J, Zheng D, Rand K, Dixon L, Moyer R, Clapp W, Lucas AR (2019). Serp-2, a virus-derived apoptosis and inflammasome inhibitor, attenuates liver ischemia-reperfusion injury in mice.
    Journal of Inflammation. 16(1), 12 (✝Equal Contributions)
  11. Yaron JR✝, Kwiecien JM✝, Zhang L✝, Ambadapadi S, Wakefield DN, Clapp WL, Dabrowski W, Burgin M, Munk BH, McFadden G, Chen H, Lucas AR (2019). Modifying the Organ Matrix Pre-Engraftment; A New Transplant Paradigm?
    Trends in Molecular Medicine 25(7), 626-639 (✝Equal Contributions)
  12. Kwiecien JM, Dabrowski W, Marzec-Kotarska B, Kwiecien-Delaney CJ, Yaron JR, Zhang L, Schutz L, Lucas AR (2019). Myxoma virus derived immune modulating proteins, M-T7 and Serp-1, reduce early inflammation after spinal cord injury in the rat model.
    Folia Neuropathologica. 57(1), 41-50
  13. Chen H, Bartee M, Yaron J, Liu L, Zhang L, Zheng D, Hogue I, Bullard W, Tibbetts S, Lucas A (2018). Mouse Gamma Herpesvirus MHV-68 Induces Severe Gastrointestinal (GI) Dilatation in Interferon Gamma Receptor-Deficient Mice (IFNγR-/-) That Is Blocked by Interleukin-10.
    Viruses. 10(10), 518
  14. Kostenko S, Heu CC, Yaron JR, Singh G, Oliveira CD, Muller WJ, Singh VP (2018). c-Src Regulates Cargo Transit via the Golgi in Pancreatic Acinar Cells.
    Scientific Reports. 8(1), 11903
  15. Chen H, Ambadapadi S, Wakefield D, Bartee MY, Yaron JR, Zhang L, Archer-Hartmann SA, Azadi P, Burgin M, Borges C, Zheng D, Ergle K, Muppala V, Morshed S, Rand K, Clapp W, Proudfoot A, Lucas A (2018). Selective Deletion of Heparan Sulfotransferase Enzyme, Ndst1, in Donor Endothelial and Myeloid Precursor Cells Significantly Decreases Acute Allograft Rejection.
    Scientific Reports. 8(1), 13433
  16. Mahon BP, Ambadapadi S, Yaron JR, Lomelino CL, Pinard MA, Keinan S, Kurnikov I, Macaulay C, Zhang L, Reeves W, McFadden G, Tibbetts S, McKenna R, Lucas AR (2018). Crystal Structure of Serp-1, a Myxomavirus-derived Immune Modulating Serpin; Structural Design of Serpin Reactive Center Loop (RCL) Peptides with Improved Therapeutic Function.
    Biochemistry. 57(7), 1096-1107
  17. Al-Ani M✝, Ambadapadi S✝, Yaron JR✝, Zheng D, Fortunel A, Doroton-Guevara M, Liu L, Morshed S, Fricker J, Miles W, McKillop M, Lucas A (2017). Atrial Fibrillation Ablation Increases Inflammation-Chemokine Modulation Suppresses Activation of Leukocytes Isolated after Ablation.
    Cardiovascular and Hematologic Disorders: Drug Targets. 17(3), 195-204 (✝Equal Contributions)
  18. Lucas A, Ambadapadi S, Mahon B, Viswanathan K, Chen H, Liu L, Dai E, Munuswami-Ramanujam G, Kwiecien JM, Yaron JR, Narute PS, McKenna R, Keenan S, Brantly M, McFadden G (2017). The Serpintine Solution.
    Journal of Clinical and Experimental Cardiology. 8(1), e150
  19. Yaron JR, Rao MY, Gangaraju S, Zhang L, Kong X, Su F, Tian Y, Glenn HL, Meldrum DR (2016). The oxindole Syk inhibitor OXSI-2 blocks nigericin-induced inflammasome signaling and pyroptosis independent of potassium efflux.
    Biochemical and Biophysical Research Communications. 472(3), 545-550
  20. Oliveira CD, Patel K, Mishra V, Trivedi RN, Noel P, Singh A, Yaron JR, Singh VP (2016). Characterization and Predictive Value of Near Infrared 2-Deoxyglucose Optical Imaging in Severe Acute Pancreatitis.
    PLoS ONE. 11(2), e0149073
  21. Yaron JR, Gangaraju S, Rao MY, Kong X, Zhang L, Su F, Tian Y, Glenn HL, Meldrum DR (2015). K+ regulates Ca2+ to drive inflammasome signaling: dynamic visualization of ion flux in live cells.
    Cell Death and Disease. 6(10), e1954
  22. Kong X, Su F, Zhang L, Yaron J, Lee F, Shi Z, Tian Y, Meldrum DR (2015). A Highly Selective Mitochondria-Targeting Fluorescent K+ Sensor.
    Angewandte Chemie International Edition. 54(41), 12053-12057
  23. Yaron JR, Ziegler CP, Tran TH, Glenn HL, Meldrum DR (2014). A convenient, optimized pipeline for isolation, fluorescence microscopy and molecular analysis of live single cells.
    Biolocal Procedures Online. 16(9)